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Software Architect (EHR, LIMS, RWE)


  • Job Type: Full-Time
  • Function: Engineering Software
  • Industry: Digital Health
  • Post Date: 04/29/2021
  • Website:
  • Company Address: 185 Dartmouth Street, Suite 502, Boston, MA, 02116


SOPHiA GENETICS combines deep expertise in life sciences and medical disciplines with mathematical capabilities in data computing. Our mission is to bring data analytics solutions to market, to support healthcare professionals by maximizing the power of Data-Driven Medicine. We achieve this mission through the global adoption of SOPHiA AI, which is built using techniques such as statistical inference, pattern recognition and machine learning. This enables SOPHiA to provide equal benefits to all users, unite experts in a gold standard health tech platform, and motivate expert knowledge sharing for a sustainable impact on future patients.

Job Description

Would you like to join an Architecture team charged with designing and developing our game changing computational platform used to deliver genomic, radiomic, and clinical data analysis to over 1000 healthcare institutions and over 500,000 cancer and rare genetic disease patients worldwide? Join our growing distributed team and use your exceptional technical skills to help us deliver on our mission of democratizing Data-Driven Medicine.

In order to augment our technical team we are looking for a Software Architect (Principal Software Development Engineer) to join our team in the US, working from home office, with occasional face-to-face meetings as needed.

As part of the Architecture team you will report directly to the Chief Architect, and will help design the future of SOPHiA DDM, our flagship software product, used to perform large-scale multi-modal analysis of patient data and deliver data-driven insights to hundreds of thousands of patients worldwide.

Our platform is a one-of-a-kind globally distributed information system that brings together hospitals and labs to provide data ingestion and processing, analysis and modeling, reporting and intelligence, distribution and sharing of a multitude of complex sources of structured and unstructured data, including genomics, imaging, and clinical data, delivered as a multi-tenant SaaS platform on the cloud.

Your principal responsibility will be to design and lead the projects enabling SOPHiA DDM to interoperate seamlessly with major hospital LIMS and EHR systems, making use of HL7, FHIR and other interoperability standards wherever possible. You will be an expert within the Architecture team and will act as the seed to grow a team of dedicated software engineers working on the implementation.

You will work closely with the Platform Product team, VP Engineering and other senior leaders to determine suitable MVP and set achievable short, mid and long-term goals.


You are an experienced software engineer, capable of designing and implementing complex systems and with extensive experience leading the development of integrations with LIMS or EHR systems, with FHIR / HL7.

You are comfortable designing for large, fault tolerant and scalable distributed systems, familiar with a broad range of microservices and modern web-based technology stacks.

You are an excellent communicator, able to explain your design choices to both management and engineers, and comfortable working remotely.

You are hands-on and are ready to rapidly develop prototypes or jump in to assist the engineering teams as necessary to further your mission.

    Bachelor’s degree in Computer Science or Engineering or equivalent professional experience
    10 years’ experience in software engineering field
    2 years in a principal software development engineer role
    In-depth knowledge of LIMS / EHR systems
    Experience designing and developing integrations with FHIR / HL7
    Experience with large-scale distributed system design
    In-depth knowledge of the JAVA ecosystem
    Excellent interpersonal and communication skills
    Experience developing software for medical devices would be an advantage
    Experience with genomics and imaging data is an asset
    Knowledge of software engineering best practices (Agile, Continuous Value Delivery, CI/CD, DevOps, NoOps, PaaS, SaaS, LEAN software, Service Oriented Architecture, cloud computing)
    Experience with formal architecture frameworks such as TOGAF


    A flexible, friendly and international working environment with a collaborative atmosphere
    An exciting company mission that brings together science and technology to directly impact the lives of patients with life threatening illness.
    A fast-growing company with plenty of opportunity for personal growth and development
    A hard technical challenge to solve with exciting modern technology - cloud computing, Big Data, DevOps, machine learning

Location: HOME OFFICE (Massachusetts and the surrounding states, 2-3h from Boston)

Start: ASAP (or as agreed)

Contract type: Permanent full-time

Application process

If you think you fit this position, please send a CV and a cover letter. Please note that incomplete applications will not be considered.

After an initial screening process, candidates will be invited for remote interviews. Selected candidates will then be invited for personal interviews.

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